Introduction of solution

Introduction  of solution

Pharmaceutical solution are defined as liquids containing one or more soluble chemical substances dissolved casually in purified water intended for internally or externally  use . Mostly purified water is used . Sometimes alcohol , diluted alcohol , glycerin or

Propylene glycol can be used as a solvent in the preparation of monophagic liquid for internal use . Purified water is the water obtained by the distillation , ion exchange treatment , or reverse osmosis or other suitable processes . It is prepared drom the drinking water which contain no added substances . Its pH should be in the range of 5 to 7 and total solids should not be more than 0.001% . Drug mixture for solution are the powder mixture of drug along with other additives except the vehcle .

Generally , there are four methods  to prepare a solution –

     i)  Solutions prepared by  simple solution   Example -  NaCl solution

    ii)  Solutions prepared by   chemical reaction . Example – Magnesium citrate solution

  iii)  Solutions prepared by simple solution with sterilization .Example – Ophthalmic solution   .

iv)  Solutions prepared by   extraction . Example – Tincture of various crude drug .

There the solutions having is called True solution  and also they are the solution having solid particles in colloidal states ( 10 to 100 A*) is called Colloidal solution  in which the particles can’t be seenb by necked eye or under ordinary microscope .